Active Pharmaceutical Ingredients (APIs)
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| Sr. No. | Name of API | Therapeutic Class |
|---|---|---|
| 1 | Benfotiamine | Diabetic Neuropathy / Dietary Supplement |
| 2 | Calcium Dobesilate Monohydrate | Diabetic Retinopathy |
| 3 | Minoxidil | Anti-hypertensive Vasodilators |
| 4 | Minoxidil Sulphate | Anti-hypertensive Vasodilators |
| 5 | Ondansetron Hydrochloride | Anti-Emetic |
| 6 | Ondansetron Base | Anti-Emetic |
| 7 | Ursodeoxycholic Acid | Gastrology |
| 8 | Valgancyclovir Hydrochloride | Anti-Viral |
| 9 | Phenobarbital | Anticonvulsant |
| 10 | Phenobarbital Sodium | Anticonvulsant |
| 11 | Deferasirox | Iron Chelators |
| 12 | Amlodipine Besilate | Antihypertensive |
| 13 | S-Amlodipine Besylate (Levamlodipine Besylate) | Antihypertensive |
| 14 | Celecoxib | NSAID |
| 15 | Etoricoxib | NSAID |
| 16 | Glibenclamide | Antidiabetic |
| 17 | Febuxostat | Xanthine Oxidase Inhibitors |
| 18 | Linagliptin | Antidiabetic |
| 19 | Vildagliptin | Antidiabetic |
| 20 | Glimepiride | Antidiabetic |
| 21 | Rivaroxaban | Anticoagulants |
| 22 | Montelukast Sodium | Leukotriene Receptor Antagonists |
| 23 | Lidocaine Base / Lidocaine HCl | Antiarrhythmic and Analgesic |
| 24 | Nizatidine | H2 Blockers |
| 25 | Nalidixic Acid IP/BP/EP/USP | Antibacterial |
| 26 | Rosuvastatin | Cholesterol Lowering |
| 27 | Carbamazepine | Anticonvulsant |
Intermediates – India Source
| Sr. No. | Intermediate Name | CAS No. | Name of API |
|---|---|---|---|
| 1 | 2,4-Diamino-6-chloropyrimidine | 156-83-2 | Minoxidil |
| 2 | 2-AminoDiphenylSufide | 1134-94-7 | Quetiapine |
| 3 | 2-Chloro-6,7-dimethoxyquinazolin-4-amine | 216699-86-4 | Alfuzosin / Prazosin |
| 4 | 1,2,3,9 Tetrahydro Carbazole | 15128-52-6 | Ondansetron / Carvedilol |
| 5 | 10-Methoxy Iminostilbene | 4698-11-7 | Oxcarbazepine |
| 6 | 4-(4-Aminophenyl)morpholine-3-one | 438056-69-0 | Rivaroxaban |
| 7 | 6-Fluoro-3,4-dihydro-(2H)-1-benzopyran-2-carboxylic acid ethyl ester | 99199-61-8 | Nebivolol |
| 8 | Amlodipine Base | 88150-42-9 | Amlodipine |
| 9 | S-Amlodipine Base (Levamlodipine Base) | 103129-82-4 | Amlodipine |
| 10 | N-{2-[4-Aminosulfonyl)phenyl]ethyl}-3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide | 119018-29-0 | Glimepiride |
| 11 | 1-(4-Methylphenyl)-4,4,4-trifluorobutane-1,3-dione | 720-94-5 | Celecoxib |
| 12 | (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile / 3-Amino-1-adamantanol | 207557-35-5 | Vildagliptin |
| 13 | (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid | 486460-00-8 | Sitagliptin |
| 14 | 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine | 762240-92-6 | Sitagliptin |
| 15 | Methyl 4-(2,4,5-trifluorophenyl)-3-oxobutanoate | 769195-26-8 | Sitagliptin |
| 16 | Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropionate | 178306-47-3 | Ambrisentan |
| 17 | 4-(Bromomethyl)-2-quinolinone | 4876-10-2 | Rebamipide |
| 18 | Diethyl Acetamidomalonate | 1068-90-2 | Rebamipide |
| 19 | 3-Chloropropylamine Hydrochloride | 6276-54-6 | Lopinavir |
| 20 | 2,6-Dimethyl Phenoxy Acetic Acid | 13335-71-2 | Lopinavir |
| 21 | 4-(Benzyloxy)-2-bromo Propiophenone | 35081-45-9 | Bazedoxifene |
| 22 | 4-Benzyloxy Aniline Hydrochloride | 51388-20-6 | Bazedoxifene |
| 23 | 5-Bromo-2-chlorobenzoic Acid | 21739-92-4 | Empagliflozin / Dapagliflozin |
| 24 | 5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide | 16673-34-0 | Glibenclamide |
| 25 | 2-(Chloromethyl)-4-methylquinazoline | 109113-72-6 | Linagliptin |
| 26 | 3-Isobutylglutaric Acid (CMH Diacid) | 75143-89-4 | Pregabalin |
| 27 | RS-(3-Carbamoylmethyl)-5-methylhexanoic Acid | 181289-52-7 | Pregabalin |
| 28 | R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic Acid (R-Amide) | 181289-33-8 | Pregabalin |
| 29 | Dibenzo-[b,f][1,4]-thiazepin-11(10H)-one (DBT / DTO) | 3159-07-7 | Quetiapine |
Intermediates – China Source
| Sr. No. | Name of the Intermediates | CAS No. | Name of API |
|---|---|---|---|
| 1 | (11β,16β)-11-Hydroxy-2′-methyl-5′H-pregna-1,4-dieno (17,16-D) oxazole-3,20-dione (D5) | 13649-88-2 | Deflazacort |
| 2 | 2-Butyl-4-chloro-5-formyl imidazole (BCFI) | 83857-96-9 | Losartan |
| 3 | 2-N-Propyl-4-methyl-6-(1-methylbenzimidazole-2-yl)benzimidazole (BIM) | 152628-02-9 | Telmisartan |
| 4 | 4-(4-Aminophenyl)morpholin-3-one | 438056-69-0 | Rivaroxaban |
| 5 | 5-Chlorothiophene-2-carboxylic acid | 24065-33-6 | Rivaroxaban |
| 6 | (S)-(+)-N-(2,3-Epoxypropyl) phthalimide | 161596-47-0 | Linezolid |
| 7 | Iminodibenzyl | 494-19-9 | Carbamazepine |
| 8 | Iminodibenzyl carbonyl chloride | 33948-19-5 | Carbamazepine |
| 9 | Iminostilbene carbonyl chloride | 33948-22-0 | Carbamazepine |
| 10 | 10-Methoxy iminostilbene | 4698-11-7 | Oxcarbazepine |
| 11 | Ofloxacin Q Acid | 82419-35-0 | Ofloxacin |
| 12 | Levofloxacin Q Acid | 100986-89-8 | Levofloxacin |
| 13 | Ethyl (2S,5R)-5-((Benzyloxy)amino)piperidine-2-carboxylate oxalate | 1416134-48-9 | Avibactam |
| 14 | (2S,5R)-5-((Benzyloxy)amino)piperidine-2-carboxamide | 1416134-49-0 | Avibactam |
| 15 | (2S,5R)-6-(Benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamide | 1192651-49-2 | Avibactam |
| 16 | (1-Butanaminium, N,N,N-tributyl-, (1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl sulfate | 1192651-80-1 | Avibactam |
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